Medical disclaimer. This page is for tracking and education only. It is not medical advice and it never recommends doses. Talk with your prescriber or care team before you change, lower, or stop any medication. Ozempic, Wegovy, Mounjaro, and Zepbound are named only to describe what readers search for.
Start with your prescriber
Coming off Mounjaro is a medication decision to make with your prescriber or care team. This guide is for tracking and education only. It does not tell you whether to stop, when to stop, or how to change a dose.
If you are tapering, have stopped, or are maintaining after tirzepatide, it can help to write down what you notice between visits. Some people track weight, appetite, strength work, and how eating feels day to day. If eating feels hard, talk to a clinician.
If you want a broader overview of what people report after stopping a GLP-1, see what happens when you stop GLP-1. If you are comparing Mounjaro with another brand name, you may also find coming off Zepbound useful, since both guides focus on tracking and trial data rather than medication instructions.
The app is planned as a place to record these notes on your device, with no account, and to export or delete everything if you want to keep a copy for your visit.
What SURMOUNT-4 reported
In SURMOUNT-4, adults who completed 36 weeks of tirzepatide and then were switched to placebo gained 14.0% of body weight from week 36 to week 88. Adults who continued tirzepatide lost a further 5.5% over the same period.
That result is often discussed by people searching for coming off Mounjaro because it shows that body weight can change after treatment is stopped, and it also shows that the trial compared continued treatment with stopping. It does not tell any one person what will happen in real life.
Trials can help frame a conversation, but they do not replace individualized care. Your prescriber can help interpret the result in the context of your health history, your current goals, and any other medicines or conditions you have.
If you want a place to keep the details you discuss, the app is planned to include a weekly weight trend with an adjustable regain band, so you can see small shifts without trying to interpret every single weigh-in. It is tracking only, not a judgment about progress.
What to track
When people are coming off Mounjaro, simple tracking can make a follow-up visit easier to use. The point is not to self-diagnose or to decide on treatment changes. It is to notice patterns you can describe clearly to your prescriber.
- Weight trend: record weekly weights if that is already part of your routine, and look at the trend rather than a single day.
- Appetite: note whether hunger feels quieter or louder than usual, and any times eating feels difficult.
- Strength work: jot down resistance sessions if you do them. The planned app includes a strength log aimed at 2 to 3 sessions a week.
- Food tolerance: write down foods that feel easier or harder to eat, especially if your appetite is changing.
- Questions and symptoms: keep a short list for your next visit so you do not have to remember it later.
The planned app also includes a weekly appetite check-in from 1, quiet, to 5, loud. That kind of scale can help you describe changes without turning them into a good or bad score.
For some people, protein and fiber are also worth tracking because these are common parts of everyday nutrition conversations. The app is planned to calculate targets from body weight, but it will not tell you what to eat or how to adjust your medication. If eating feels hard, talk to a clinician.
If you are interested in how a taper timeline is tracked, the app is planned to let you type in dose steps you were given. It will not calculate, validate, or suggest any dose schedule. For a broader overview of that topic, see GLP-1 taper schedule.
The planned app will store data on the device, with no account. It is meant to support notes you can bring to a visit, not to replace medical care.
Questions to bring to your visit
It can help to bring a short list of questions. You do not need a perfect plan before the appointment. A few clear notes are often enough to start the conversation.
- What should I watch for after stopping or tapering?
- How should I share changes in appetite, weight, or strength with you?
- Are there specific symptoms that should prompt me to contact your office sooner?
- What would you like me to track before the next visit?
- How do my other conditions or medicines affect this conversation?
You can also ask whether your care team wants you to bring weekly logs or just a summary of the main changes. If you are using the app, its planned export feature could make that easier by putting your notes in one place.
Coming off Mounjaro can mean very different things from one person to another. The most useful next step is usually not trying to interpret every change on your own, but bringing a small, honest record to a clinician who knows your history.
If you want to keep reading, the related guides on what happens when you stop GLP-1 and coming off Zepbound may help you prepare for that conversation.
Join the iOS waitlist from Get the app.
Key facts
- In SURMOUNT-4 (JAMA 2024), from week 36 to week 88 people switched to placebo gained 14.0% of body weight, while those who continued tirzepatide lost a further 5.5%. Source
Sources
Last updated: